Magnetic materials are expected to be used for cancer treatment
A special type of magnetic material that achieves a specific self-regulating heating effect and is expected to provide a new way of thinking for the treatment of cancer by hyperthermia. The researchers said, “This intense self-regulating thermal effect is unmatched by other materials, and it is expected to open a high temperature treatment of cancer in the body to bring a new design strategy.
A special type of magnetic material that achieves a specific self-regulating heating effect and is expected to provide a new way of thinking for the treatment of cancer by hyperthermia.
Temperatures that can be tolerated by healthy cells of the body have long been considered to be useful for destroying cancer cells. A method of using magnetic particles, introduced into tissues and remotely heated, has achieved certain success in cancer treatment. But this technical distance has a certain distance to become a standardized procedure.
Magnetic materials are expected to be used for cancer treatment
One problem that hinders the development of this technology is the insufficient heat capacity of the magnetic particles. However, a research team led by Professor Kiyonori Suzuki of Monash University discovered a new type of material that not only can be heated quickly, but can also be quickly blocked so that it does not overheat.
More importantly, the magnetic particles reach a temperature sufficient to kill the tumor tissue, but are too low for normal healthy body tissues to affect normal body tissues.
“The heat effect of this strong self-regulation is unmatched by other materials,” Professor Suzuki said. “It is hoped that opening the body to treat cancer at high temperatures will bring a new design strategy.”
The research team is made up of other research members from the University of Monash, as well as Professor Karl G Sandeman of the City University of New York and Brooklyn College of London. What the research team is currently working on is a magnetocaloric material called a first-order magnetic material, which is mainly used for magnetic refrigeration.
The nature of these materials is that they are limited by their Curie temperature, i.e., the magnetic properties change at this temperature point. For different materials, the Curie temperature is different.
“We chose these materials for research because their Curie temperature is within the ideal temperature range for cancer hyperthermia,” said Professor Suzuki.
The first-order Curie transition is a key factor in the particularly large heating power. This is different from the traditional Curie transition in which the traditional two magnetic states coexist. Due to the complex cause of this coexistence, the external magnetic field is most converted to heat near the Curie temperature – and then above the Curie temperature, this switching effect stops abruptly.
Researchers hope that their proof-of-concept research published in Applied Physics Letters will open the way for cancer treatment.
Due to the superior thermal effects, these first-order magnetic materials are expected to be a minimally invasive, inexpensive method of intracellular hyperthermia.
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